Prescription Drugs. Doctor's advices on take a drugs - Description, Interactions, Side Effects. Online
Drugs by First Letter:  A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Prescription Drugs 24.com main page News
 
 
  Medical Services  
  Home  
  From A to Z Drug List  
  Drugs by Condition  
   
 
 
  Top 10 Search Drugs by Condition  
   
   
   
   
   
   
   
   
   
   
   
     
 
  Top 100 Popular Drugs  
Abilify
Accutane
Actiq
Actonel
Adderall
Advair
Alimta
Allegra
Alli
Ambien
Amitiza
Aricept
Avandia
Avodart
Boniva
Botox
Byetta
Caduet
Celebrex
Celexa
Chantix
Cialis
Claritin
Coumadin 
Crestor
cyclobenzaprine
Cymbalta
Diovan
Effexor
Emend
Enbrel
ephedrine
Femara
fish oil
Flomax
folic acid
Fosamax
gabapentin
Gardasil
Geodon
Insulin
Juvederm
Keppra
Lamictal
Lasix
Levaquin
Levitra
Lexapro
Lipitor
lisinopril
lithium
Lotrel
Lunesta
Lyrica
Melatonin
metformin
methadone
methotrexate
Mirapex
Mirena
Namenda
naproxen
Nasonex
Neurontin
Nexium
niacin
Norco
Norvasc
omeprazole
Orencia
Ortho Evra
oseltamivir
oxycodone
oxycontin
Paxil
Percocet
phentermine
Plan B
Plavix
prednisone
Prevacid
Prilosec
promethazine
Propecia
Protonix
Provigil
Prozac
Pulmicort 
Restylane
Rogaine
Seroquel
simvastatin
Singulair
Soma
Spiriva
Suboxone
Synvisc
Tamiflu
tamoxifen
Taxol
testosterone
thyroid
Topamax
tramadol
trazodone
Ultram
Valtrex
Viagra
Vicodin
Vioxx
Vytorin
Wellbutrin
Xanax
Xenical
Yasmin
Yaz
Zelnorm
Zetia
Zocor
Zoloft
Zyprexa
Zyrtec
ADVERTISEMENT
     
     
     
 
  Support Services  
About US
Contact US
Helpful Resources
Pharmaceutical Companies
Terms of Use
Privacy Policy
This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
Verify here
 
  Back  
 

Ampicillin and sulbactam

 
  Generic Name: Ampicillin and sulbactam (am pi SIL in and sul BAK tam)
 
  Brand Names: Unasyn  
     
   
 

What is ampicillin and sulbactam?

Ampicillin and sulbactam are antibiotics in the penicillin group of drugs. They fight bacteria in your body.

The combination of ampicillin and sulbactam is used to treat many different types of infections caused by bacteria.

Ampicillin and sulbactam may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about ampicillin and sulbactam?

Do not use this medication if you are allergic to ampicillin and sulbactam or to any other penicillin antibiotic, such as amoxicillin (Amoxil), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.

Before using ampicillin and sulbactam, tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others, or if you have asthma, kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or a history of any type of allergy.

Ampicillin and sulbactam can make birth control pills less effective, which may result in pregnancy. Before using ampicillin and sulbactam, tell your doctor if you use birth control pills. Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Ampicillin and sulbactam will not treat a viral infection such as the common cold or flu. Do not give this medication to another person, even if they have the same symptoms you do.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

What should I discuss with my healthcare provider before using ampicillin and sulbactam?

Do not use this medication if you are allergic to ampicillin and sulbactam or to any other penicillin antibiotic, such as:

  • amoxicillin (Amoxil, Amoxicot, Biomox, Dispermox, Trimox);

  • carbenicillin (Geocillin);

  • dicloxacillin (Dycill, Dynapen);

  • oxacillin (Bactocill); or

  • penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).

Before using ampicillin and sulbactam, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:

  • kidney disease;

  • a bleeding or blood clotting disorder;

  • mononucleosis (also called "mono");

  • a history of diarrhea caused by taking antibiotics; or

  • a history of any type of allergy.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Ampicillin and sulbactam can make birth control pills less effective, which may result in pregnancy. Before using ampicillin and sulbactam, tell your doctor if you use birth control pills. Ampicillin and sulbactam can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use ampicillin and sulbactam?

Ampicillin and sulbactam is given as an injection into a muscle or through an IV needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. When it is given as an IV injection, this medicine must be given slowly, and can take up to 30 minutes to complete.

You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using ampicillin and sulbactam.

Store ampicillin and sulbactam at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, behavior changes, a severe skin rash, urinating less than usual, or seizure (black-out or convulsions).

What should I avoid while using ampicillin and sulbactam?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Ampicillin and sulbactam side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

  • diarrhea that is watery or bloody; or

  • fever, chills, body aches, flu symptoms.

Less serious side effects may include:

  • nausea, vomiting, stomach pain, bloating, gas;

  • vaginal itching or discharge;

  • headache;

  • itching;

  • swollen, black, or "hairy" tongue;

  • thrush (white patches or inside your mouth or throat); or

  • pain, swelling, or other irritation where the needle is placed.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Ampicillin and sulbactam Dosing Information

Usual Adult Dose for Aspiration Pneumonia:

1.5 to 3 g IV every 6 to 8 hours. Parenteral therapy should continue until the patient's condition stabilizes, at which time appropriate oral antimicrobial therapy may be initiated.

Therapy of documented anaerobic pleuropulmonary infections should be continued until after the infiltrate has been cleared, or a residual scar forms, sometimes requiring as long as 2 to 4 months.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Deep Neck Infection:

1.5 to 3 g IV or IM every 6 to 8 hours. Parenteral therapy should continue until the patient's condition stabilizes, at which time appropriate oral antimicrobial therapy may be initiated.

Therapy should continue for 2 to 3 weeks, depending on the nature and severity of the infection.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Epiglottitis:

1.5 to 3 g IV every 6 to 8 hours. Parenteral therapy should continue until the patient's condition stabilizes, at which time appropriate oral antimicrobial therapy may be initiated.

Therapy should continue for 7 to 10 days, depending on the nature and severity of the infection.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Intraabdominal Infection:

1.5 to 3 g IV every 6 to 8 hours for 7 to 14 days, depending on the nature and severity of the infection.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Joint Infection:

1.5 to 3 g IV or IM every 6 to 8 hours for 3 to 4 weeks, depending on the nature and severity of the infection. Longer therapy, for 6 weeks or more, may be required for prosthetic joint infections.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Osteomyelitis:

1.5 to 3 g IV or IM every 6 to 8 hours for 4 to 6 weeks, depending on the nature and severity of the infection. Chronic osteomyelitis may require additional oral antibiotic therapy, possibly for up to 6 months.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Pelvic Inflammatory Disease:

1.5 to 3 g IV or IM every 6 to 8 hours. Parenteral therapy should be continued for at least 48 hours after clinical signs of improvement are observed. Oral therapy may then be substituted to complete a 14 days course.

Oral doxycycline therapy for 7 days should be considered to treat possible concurrent chlamydia infection in males and nonpregnant females. Evaluation of the patient's sexual partner(s) is also recommended.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Peritonitis:

1.5 to 3 g IV every 6 to 8 hours for 10 to 14 days, depending on the nature and severity of the infection.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Pneumonia:

1.5 to 3 g IV or IM every 6 to 8 hours. Therapy should continue for 7 days if pneumococcal pneumonia is suspected and up to 21 days if other organisms are responsible.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Pyelonephritis:

1.5 to 3 g IV or IM every 6 to 8 hours. Parenteral therapy should continue until the patient is clinically stable at which time, oral therapy may be instituted and continued until a 14 day course of treatment has been completed.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Skin or Soft Tissue Infection:

1.5 to 3 g IV or IM every 6 to 8 hours for 7 to 10 days, or for 3 days after acute inflammation resolves, depending on the nature and severity of the infection.

For more severe infections, such as diabetic soft tissue infections, 14 to 21 days of therapy may be required.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Surgical Prophylaxis:

1.5 to 3 g IV or IM once shortly before induction of anesthesia. The dose may be continued every 6 hours for 24 hours if desired.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Adult Dose for Urinary Tract Infection:

1.5 g IV or IM every 6 hours for 3 to 7 days, depending on the nature and severity of the infection.

Dosages expressed reflect the combined ampicillin and sulbactam components (in a constant 2:1 ratio).

Usual Pediatric Dose for not applicable:

1 month to 1 year:
Mild to moderate infection: 25 to 37.5 mg/kg (ampicillin) IV every 6 hours
Severe infection: 50 to 75 mg/kg (ampicillin) IV every 6 hours

>1 year to 12 years:
Mild to moderate infection: 25 to 50 mg/kg (ampicillin) IV every 6 hours
Severe infection: 50 to 100 mg/kg (ampicillin) IV every 6 hours

Usual Pediatric Dose for Meningitis:

1 month to 1 year: 50 to 75 mg/kg (ampicillin) IV every 6 hours

>1 year to 12 years: 50 to 100 mg/kg (ampicillin) IV every 6 hours
Maximum dose: 8 g ampicillin/24 hours

What other drugs will affect ampicillin and sulbactam?

Before using ampicillin and sulbactam, tell your doctor if you are using any of the following drugs:

  • allopurinol (Zyloprim);

  • probenecid (Benemid); or

  • an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), netilmicin (Netromycin), streptomycin, tobramycin (Nebcin, Tobi).

This list is not complete and there may be other drugs that can interact with ampicillin and sulbactam. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about ampicillin and sulbactam.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.04. Revision Date: 4/12/2009 4:35:49 PM.;
 
 
 
Drugs by First Letter:  A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 
Copyright © Prescription-Drug-24.com