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Ferumoxsil

 
  Generic Name: Ferumoxsil (fer yoo MOX il)
 
  Brand Names: GastroMARK  
     
   
 

What is ferumoxsil?

Ferumoxsil is in a group of drugs called imaging contrast agents. Ferumoxsil contains iron, a substance that is magnetic. Contrast agents are used to allow certain internal organs to be seen clearly on an MRI (magnetic resonance imaging).

Ferumoxsil is used to help diagnose certain disorders of the stomach or intestines.

Ferumoxsil may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about ferumoxsil?

Do not receive this medication if you are allergic to ferumoxsil, or if you have a blocked or perforated intestine.

Before receiving this medication, tell your doctor if you are allergic to any drugs, if you have an iron overload disorder (such as chronic hemolytic anemia) or if you have received frequent blood transfusions. Also tell your doctor if you have a history of hiatal hernia, gastroesophageal reflux disease (GERD), inflammatory bowel disease, or if you have recently had any nausea, vomiting or diarrhea.

After receiving ferumoxsil, call your doctor at once if you have severe stomach pain or cramping, or a skin rash with bruising, severe tingling, numbness, pain, and muscle weakness.

Less serious side effects are more likely to occur, such as mild stomach pain, nausea, vomiting, diarrhea, headache, or numbness and tingling of your mouth.

What should I discuss with my health care provider before receiving ferumoxsil?

Do not receive this medication if you are allergic to ferumoxsil, or if you have a blocked or perforated intestine.

Before receiving this medication, tell your doctor if you are allergic to any drugs, or if you have:

  • an iron overload disorder such as chronic hemolytic anemia;

  • a history of frequent blood transfusions;

  • a history of hiatal hernia;

  • gastroesophageal reflux disease (GERD);

  • inflammatory bowel disease;

  • if you tend to burp up food, especially when lying down after a meal; or

  • if you have recently had any nausea, vomiting, or diarrhea.

If you have any of these conditions, you may not be able to receive ferumoxsil.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ferumoxsil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is ferumoxsil used?

Ferumoxsil is a liquid that you will be asked to drink before your MRI is performed.

Ferumoxsil must be taken on an empty stomach. You will need to fast (not eat or drink anything) for at least 4 hours before you take this medicine.

In some cases, the MRI will be done within 30 minutes after you drink the ferumoxsil. However, you may be asked to drink the liquid several hours before your MRI. Follow your doctor's instructions.

What happens if I miss a dose?

Since ferumoxsil is used only for the purposes of your MRI, you will not be on a dosing schedule.

What happens if I overdose?

Contact your doctor if you think you have received too much of this medication. Symptoms of a ferumoxsil overdose are not known.

What should I avoid while taking ferumoxsil?

On the day of your MRI, avoid foods or beverages that upset your stomach. Ferumoxsil can cause mild to severe stomach discomfort.

Ferumoxsil side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • severe stomach pain or cramping; or

  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects are more likely to occur, such as:

  • mild stomach pain, nausea, vomiting, diarrhea;

  • upset stomach;

  • skin rash or itching;

  • headache; or

  • numbness or tingling in or around your mouth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ferumoxsil?

Before receiving this medication, tell your doctor if you are using iron supplements.

There may be other drugs that can affect ferumoxsil. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your doctor has information about ferumoxsil written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 4/12/2009 4:46:06 PM.;
 
 
 
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