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Protonix

 
  Generic Name: Pantoprazole (pan TOE pra zole)
 
  Brand Names: Protonix  
     
   
 

What is Protonix?

Protonix is in a group of drugs called proton pump inhibitors. It decreases the amount of acid produced in the stomach.

Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome.

Protonix may also be used for purposes other than those listed in this medication guide.

Important information about Protonix

Do not stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated. Do not crush, chew, or break a delayed-release (enteric-coated) tablet. It is specially made to release the medicine slowly into your body.

The oral granules should be mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food. Protonix granules may also be given with apple juice through a nasogastric (NG ) tube.

Some conditions must be treated long-term with Protonix. The chronic use of Protonix has caused stomach cancer in animal studies, but it is not known if Protonix would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.

Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.

What should I discuss with my healthcare provider before taking Protonix?

Do not take Protonix if you are allergic to pantoprazole. Before taking Protonix, tell your doctor if you are allergic to any drugs.

Some conditions must be treated long-term with Protonix. The chronic use of Protonix has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.

Long-term treatment with Protonix may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Symptoms of a vitamin B-12 deficiency may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Talk with your doctor if you need long-term Protonix treatment and you have concerns about vitamin B-12 deficiency.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether pantoprazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Protonix?

Take Protonix exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Protonix can be taken with or without food.

Do not crush, chew, or break a delayed-release (enteric-coated) tablet. Swallow the pill whole. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating, causing too much of the drug to be released at one time.

The oral granules should be mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food. Sprinkle the granules directly onto a teaspoon of applesauce and swallow this mixture right away without chewing. Or pour the granules into a cup with 1 teaspoon of apple juice, stir for 5 seconds and swallow right away. To make sure you get the entire dose, add a little more apple juice to the same glass, swirl gently and drink right away. Do not save the granule mixture for later use.

To give Protonix granules through a nasogastric (NG) feeding tube:

  • Attach a 60-milliliter syringe to the NG tube and remove the plunger. Hold the syringe high enough to prevent any bends in the tube.

  • Sprinkle the Protonix granules into the syringe barrel and mix in 2 teaspoons of apple juice. Gently tap or shake the syringe as it empties into the tube.

  • Add another 2 teaspoons of apple juice to the syringe to help rinse the granules through and to make sure the entire Protonix dose is given. Tap or shake the syringe as the juice empties into the tube.

  • Repeat the rinse with 2 teaspoons of apple sauce at least twice more, gently shaking the syringe as it empties into the tube. Make sure there are no granules remaining in the syringe or NG tube.

Do not stop taking Protonix even if you begin to feel better. Your symptoms may improve before the condition is fully treated. Call your doctor if your condition does not improve after 8 weeks of treatment. Store Protonix at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Protonix is not expected to produce life-threatening symptoms.

What should I avoid while taking Protonix?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Protonix.

Protonix side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely to occur, such as:

  • nausea, vomiting;

  • gas, stomach pain;

  • diarrhea; or

  • headache.

Side effects other than those listed here may also occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Protonix?

Before taking Protonix, tell your doctor if you are using any of the following drugs:

  • ampicillin (Omnipen, Principen);

  • atazanavir (Reyataz);

  • a blood thinner such as warfarin (Coumadin);

  • clopidogrel (Plavix);

  • ketoconazole (Nizoral); or

  • iron (Feosol, Mol-Iron, Fergon, Femiron, others).

This list is not complete and there may be other drugs that can interact with Protonix. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about Protonix.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2009 Cerner Multum, Inc. Version: 4.02. Revision Date: 4/12/2009 4:44:11 PM.;
 
 
 
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